Cold Laser Controlled Double Blind Studies

Following is a list of cold laser controlled, randomized, double-blind studies,* which have shown that Cold Laser Therapy is an effective treatment modality for a
wide range of treatment indications such as:

Acne vulgaris
Achilles tendonitis
Ankle sprains
Carpal tunnel syndrome
Chronic back pain
Chronic neck pain
Herpes simplex
Myofascial pain syndrome
Oral mucositis
Shoulder pain
Sports injuries
Temporomandibular dysfunction

*Achilles tendinitis: Bjordal, J.M., et al. (2006). A randomized, placebo
controlled trial of low level laser therapy for activated Achilles tendinitis
with microdialysis mea-

surement of peritendinous prostaglandin E2 concentrations. British
Journal of Sports Medicine
40, pp. 75-80.

Acne vulgaris: Seaton, E.D., et al. (2003). Pulsed-dye laser

treatment for inflammatory acne vulgaris: randomised
controlled trial. The Lancet
362, pp. 1347-1352. Acute pain
style=’font-size:10.0pt;font-family:Arial’> (Review paper): Bjordal, J.M., et
al. (2006). Low-Level Laser

Therapy in Acute Pine: A Systematic Review of Possible Mechanisms
of Action and Clinical Effets in Randomized Placebo-Controlled Trials. Photomedicine
and Laser Surgery

24(2), pp. 158-168.

Carpal tunnel syndrome: Ekim, A., et al. (2007). Effect of low level laser
therapy in rheumatoid arthritis patients with carpal tunnel syndrome. Swiss

Medical Weekly 23-24, pp. 347-352.

Chronic neck pain: Chow, R.T., et al. (2006). The effect of 300 mW, 830 nm
laser on chronic neck pain: A double-blind, randomized,

placebo-controlled study. Pain
style=’font-size:10.0pt;font-family:Arial’> 124(1-2), pp. 201-210.

Herpes simplex: Schindl, A., and Neumann, R. (1999). Low-Intensity Laser
Therapy is an Effective Treatment for

Recurrent Herpes Simplex Infection. Results from a
Randomized Double-Blind Placebo-Controlled Study. Investigative Dermatology

style=’font-size:10.0pt;font-family:Arial’> 113, pp. 221-223.

Myofascial Pain Syndrome
style=’font-size:10.0pt;font-family:Arial’>: Gur, A., et al. (2004). Efficacy
of 904 nm Gallium Arsenide Low Level Laser Therapy in the Management of Chronic
Myofascial Pain in the Neck: A Double-Blind

and Randomize-Controlled Trial. Lasers in Surgery and
35, pp.

Oral mucositis:Bensadoun, R.J., et al. (1999). Low-energy He/Ne laser in
the preven-

tion of radiation-induced mucositis – A multicenter phase
III randomized study in patients with head and neck cancer. Support Care
7, DOI

Osteoarthritic knee pain
style=’font-size:10.0pt;font-family:Arial’> (Review paper): Bjordal, J.M., et
al. (2007). Short-term efficacy of physical interventions in osteoarthritic
knee pain. A systematic review and

meta-analysis of randomised placebo-controlled trials. BNC
Musculoskeletal Disorders
, DOI 10.1186/1471-2474-8-51.

Postmastectomy lymphedema
style=’font-size:10.0pt;font-family:Arial’>: Carati, C.J.,

et al. (2003). Treatment of Postmastectomy Lymphedema with
Low-Level Laser Therapy. American Cancer Society,

style=’font-size:10.0pt;font-family:Arial’> DOI 10.1002/cncr.11641.

Stroke: Lampl, Y., et al.

(2007). Infrared Laser Therapy for Ischemic Stroke: A new
Treatment Strategy. Results of the NeuroThera Effectiveness and Safety Trial-1
(NEST-1). Stroke
DOI 10.1161/


Tendinitis and Myofascial Pain Syndrome
style=’font-size:10.0pt;font-family:Arial’>(includes Epicondylitis,
trochanteritis, etc):
Lögdberg-Andersson, M., et al. (1997). Low Level

Laser Therapy (LLLT) of Tendinitis and Myofascial Pains – A
Randomized, Double-Blind, Controlled Study. LLLT

style=’font-size:10.0pt;font-family:Arial’> 9, pp. 79-86.

Tinnitus: Gungor, A., et al. (2007). Effectiveness of transmeatal low power laser irradiation for chronic tinnitus. The Journal of Laryngology & Otology, DOI 10.1017/S0022215107009619

Tags: Blog/News · Cold Laser Clinical Studies · Cold Laser Medical Studies Data · Cold Laser Therapy Education · Health and Light News

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